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Caution should be observed in patients with severe cerebral arteriosclerosis and hypotension.
Effects on ability to drive and use machines: Patients may develop dizziness when first using Isosorbide-5-mononitrate (IMDUR DURULES). Patients should be advised to determine how they react to Isosorbide-5-mononitrate (IMDUR DURULES) before they drive or operate machinery.
